Credits 4 ECTS 6

Preview of the cell and evolution theory; the chemistry of life; macromolecules; cells and organelles; membrane structure; transport across membrane; endomembrane system; bioenergetics; enzymes; chemical energy metabolism; aerobic respiration; photosysnthesis; cytoskeletal systems.

Prerequisite:none

Credits 4 ECTS 6

Cellular movement and mobility; cell adhesion; extracellular matrix; electrical and chemical signal transduction; DNA, chromosomes, nucleus; cell cycle, DNA replication, mitosis; sexual reproduction, meiosis, recombination; Mendelian genetics; gene expression; recombinant DNA technology and its applications.

Prerequisite:none

Credits 2 ECTS 3

Scientific report writing; light microscopy, gram staining; preparation of buffers and solutions; spectrophotometric measurements; bacterial growth curve; sterile techniques; extraction of DNA; agarose gel electrophoresis; organelle fractionation and analysis of subcellular fractions; transfection of eukaryotic cells; subcellular localization of proteins using fluorescent tags; mitosis; cell cycle analysis.

Prerequisite:Corequisite: BIO 102

Credits 1 ECTS 1

Historical development of molecular biology; introduction to current topics in the field such as biotechnology, cloning, and gene therapy.

Prerequisite:none

Credits 3 ECTS 5

Biochemistry of the cell; cell structure and function; photosynthesis and respiration; cytokinesis; mitosis and meiosis; Mendelian genetics; genes and chromosomes; molecular basis of inheritance; recombinant DNA technology and genetic engineering.

Prerequisite:offered to: all Social Sciences and Engineering Departments

Credits 3 ECTS 5

Origin and characteristics of life; biological macromolecules; eukaryotic and prokaryotic cell structure; membrane structure and function; cytokinesis; mitosis and meiosis; genes, chromosomes and heredity; homeostatic control mechanisms; nervous system; conscious brain and behavior; sensory system; endocrine system.

Prerequisite:offered to: Psychology and Psychological Counseling

Credits 3 ECTS 6

Darwinian perspective of evolution, phylogeny, sources of genetic diversity, natural selection, genetic drift, gene flow, population genetics, species concept, history of life on earth, tree of life, animal, plant and microbial diversity, ecology.

Prerequisite:none

Credits 3 ECTS 6

Measurements; Data analysis and organization; Biological and Statistical variables; Samples and populations; Descriptive statistics: central tendency, dispersion, standard error, confidence limits; Graphical display of data; Concepts of probability; Probability distributions; Hypothesis testing and inference: exact binomial tests, Chi-square tests, goodness of fit tests, Fisher’s test, Student’s t-test, ANOVA, MANOVA, Kruskal-Wallis test, Rank tests; Regression; Correlation; Contingency tables; Power analysis.

Credits 3 ECTS 6

Genes, genomes and genetic analysis; DNA structure and genetic variation; Mendelian genetics and its applications; chromosomes and sex-chromosome inheritance; genetic linkage; chromosome mapping, human karyotypes, chromosome behavior; extranuclear inheritance, molecular evolution, population genetics.

Credits 3 ECTS 6

Use of restriction enzyme digestion in genetic linkage analysis; Drosophila as a model organism; monohybrid and dihybrid cross; polytene chromosome and karyotype analysis; polygenic inheritance and complex traits; fluorescence in situ hybridization, (FISH); bacterial conjugation and transduction; complementation; candidate gene approach.

Prerequisite:Corequisite: BIO 252

Credits 4 ECTS 6

Molecules of life; structure and function of proteins; nucleic acids; DNA as genetic material; flow of genetic information; enzymes; membrane structure and dynamics; membrane channels and pumps.

Credits 4 ECTS 6

Catabolism and generation of phosphate bond energy; glycolysis; TCA cycle; oxidative phosphorylation; oxidation of fatty acids and oxidative degradation of amino acids; photosynthesis; biosynthesis of carbohydrates, lipids, amino acids and nucleotides.

Credits 1 ECTS 2

Introduction to understanding and interpretation of research articles in the areas of molecular biology and genetics.

Credits 4 ECTS 6

Analysis of cells, molecules and systems. Visualization of cells and their molecules. Intracellular organization and sorting. Intracellular membrane traffic. Cell signaling. Function and dynamics of the cytoskeleton. The cell cycle.

Prerequisite:BIO 102

Credits 3 ECTS 6

Cell death. Cell junctions and the extracellular matrix. Cancer. Development of multicellular organisms. Stem cells in tissue homeostasis and regeneration. The innate and adaptive immune systems.

Prerequisite:BIO 102, BIO 311

Credits 1 ECTS 2

Presentations on the current research projects carried out in the Department.

Credits 3 ECTS 6

Determination of pK of amino acids, cell disruption techniques, centrifugation techniques, sucrose gradient centrifugation, dialysis, chromatography techniques, SDS- PAGE electrophoresis; spectrophotometric measurement of protein and nucleic acid concentration; determination of protein amounts by Bradford assay, Western Blotting; thinlayer chromatography; Michaelis Menten kinetics

Prerequisite:Corequisite: 301

Credits 3 ECTS 6

Homeostatic control mechanisms; nerve cell physiology; central nervous system; peripheral nervous system; muscle physiology; cardiovascular physiology; blood and hematopoiesis; respiration and gas exchange; the kidneys; fluid and electrolyte balance; digestion and absorption of food; metabolism and energy balance; endocrine system; endocrine control of metabolism

Credits 4 ECTS 6

Chemistry of the gene; DNA replication and recombination; transcription; translation; mutation; control of gene regulation; transposable elements; genetics of bacteria and phages; gene cloning and manipulation.

Prerequisite:BIO 102

Credits 3 ECTS 6

How to use databases; primer design; construction of bacterial growth curves; competant bacterial cell preparation; plasmid DNA isolation; agarose gel electrophoresis; Polymerase Chain Reaction (PCR); purification of plasmid vector and PCR products, digestion with restriction enzymes, ligation, and transformation; screening with colony PCR; transfection of eukaryotic cells with the vector; microscopic visualization of fluorescently tagged proteins; quantitative Real Time PCR and DNA sequencing.

Prerequisite:Corequisite: BIO 353

Credits 2 ECTS 3

Responsible conduct of research (RCR): Collaborative Science, Conflicts of interests and commitment; data acquisition, management, sharing and ownership, ethical regulations in research involving human and animal subjects, mentoring; Peer review Publication practices and responsible authorship; research misconduct.

Credits 2 ECTS 3

Student presentation and discussions of research articles covering various areas of molecular biology and genetics such as development, cancer, genomics.

Credits 3 ECTS 6

Nature of cancer; oncogenes and tumor suppressor genes; signaling pathways in cancer; dysregulation of cell cycle and apoptosis; steps in tumorigenesis; treatment of cancer.

Credits 3 ECTS 6

Basic concepts in immunology; principles of innate and adaptive immunity; the generation of lymphocyte antigen receptors; development of B and T lymphocytes; antigen presentation; survival and maturation of B and T lymphocytes in peripheral tissues; T cell-mediated immunity; the humoral immune response.

Credits 3 ECTS 6

Principles of enzyme catalysis; transition state theory; basic equations of enzyme kinetics; steady-state and pre-steady state kinetics; irreversible and reversible enyme inhibition; enzymatic rate constants; rate determining processes; practical methods to determine kinetics and equilibriums; determination of intermediates in enzymatic reactions; usage of binding energy in catalysis; enzyme specificity and accuracy; editing or proofreading mechanisms; cost of accuracy in enzymatic reactions.

Credits 3 ECTS 6

Cellular and structural components of the nervous system; electrical signaling in nerve cells; action potential propagation; synaptic transmission; structure and function of ion channels; sensory systems; development of the nervous system; neuronal plasticity; learning and memory; consciousness and behavior; emotions; nervous system disorders.

Credits 3 ECTS 6

Mapping and sequencing of genomes; history and structure of genomic diversity; genomics of human diversity and disease; genomic technologies; introduction to systems biology.

Credits 3

Hidden Markov models; optimization algorithms; classification clustering algorithms and their application in identification of motives, expression, methylation, microRNA and TF regulation mechanisms

Credits 3 ECTS 6

Patterns of development; life cycles of model organisms and experimental techniques; morphogenesis; germ cells and fertilization; cell differentiation and stem cells; organogenesis; development of the nervous system; growth and post-embryonic development; regeneration; evolution.

Credits 3 ECTS 6

Genetic basis of inherited disorders; identification and characterization of novel genes; multifactorial disorders; molecular diagnosis; gene therapy.

Credits 3 ECTS 6

Structures of nuclear and cytoplasmic genomes; gene transfer techniques; gene expression and regulation in flowering plant development; transgenic plants and their use in biotechnology.

Credits 3 ECTS 6

Diversity of microorganisms and their activities; interaction of microorganisms with their microbial environment; use of microorganisms in biotechnology.

Credits 3 ECTS 6

Designed for individual students to carry out laboratory research projects under the supervision of a faculty member. A final presentation of the work is required.

Credits 3 ECTS 6

Designed for individual students to carry out laboratory research projects under the supervision of a faculty member. A final presentation of the work is required.