Academic Program
First Year
1st Semester
Course Code
Course Name
Credit
ECTS
BIO 101
Cellular and Molecular Biology I
Preview of the cell and evolution theory; the chemistry of life; macromolecules; cells and organelles; membrane structure; transport across membrane; endomembrane system; bioenergetics; enzymes; chemical energy metabolism; aerobic respiration; photosysnthesis; cytoskeletal systems. Prerequisitenone
4
6
BIO 111
Prelude to Molecular Biology
Historical development of molecular biology; introduction to current topics in the field such as biotechnology, cloning, and gene therapy. Prerequisitenone
1
1
CHEM 101
General Chemistry I
Fundamental concepts of chemistry; atomic structure, periodic trends, chemical bonding, gases, liquids, solids, solutions. Prerequisitenone
3
6
HSS / AE
Humanities or Social Science Elective /Advanced English
Students whose Proficiency Exam scores are C are required to take AE 101 or AE 102, while students whose Proficiency Exam scores are C+ are required to take AE 111 or AE 112. Students whose Proficiency Exam scores are A or B are required to take an HSS Elective course with a minimum of 3 credits. see https://registration.boun.edu.tr/ for a full list of HSS courses
3
5
MATH 101
Calculus I
Functions, limits, continuity, differentiation and applications, integration, fundamental theorem of calculus, techniques and applications of integration, improper integrals and series, Taylor polynomials, power series, basic transcendental functions. Prerequisitenone
4
6
PHYS 101
Physics I
Vectors, kinematics, Newton’s laws of motion, work and energy, conservation of energy, linear momentum and its conservation, rotation of rigid bodies about a fixed axis, angular momentum and its conservation. (One laboratory session every week).
4
8
2nd Semester
Course Code
Course Name
Credit
ECTS
BIO 102
Cellular and Molecular Biology II
Cellular movement and mobility; cell adhesion; extracellular matrix; electrical and chemical signal transduction; DNA, chromosomes, nucleus; cell cycle, DNA replication, mitosis; sexual reproduction, meiosis, recombination; Mendelian genetics; gene expression; recombinant DNA technology and its applications. Prerequisitenone
4
6
BIO 106
Cell Biology Laboratory
Scientific report writing; light microscopy, gram staining; preparation of buffers and solutions; spectrophotometric measurements; bacterial growth curve; sterile techniques; extraction of DNA; agarose gel electrophoresis; organelle fractionation and analysis of subcellular fractions; transfection of eukaryotic cells; subcellular localization of proteins using fluorescent tags; mitosis; cell cycle analysis. PrerequisiteCorequisite: BIO 102
2
3
CHEM 102
General Chemistry II
Fundamental topics in chemistry; thermochemistry, thermodynamics, kinetics, equilibrium, acids and bases, solubility equilibrium, electrochemistry.
3
6
CHEM 106
General Chemistry Laboratory
A short history of chemistry, its development and contribution to humanity; basic laboratory skills and their application to the understanding of matter and its properties. Corequisite: CHEM 102
2
4
MATH 102
Calculus II
Vector calculus, functions of several variables, directional derivatives, gradient, Lagrange multipliers, multiple integrals and their applications, change of variables, coordinate systems, line integrals, Green's theorem, divergence theorem, Stokes' theorem. PrerequisiteMATH 101
4
6
PHYS 102
Physics II
Equilibrium of rigid bodies, oscillations, gravitation, fluid statics and dynamics, waves in elastic media, introduction to thermodynamics and kinetic theory, sound. (One laboratory session every week) PrerequisitePHYS 101
4
8
Second Year
1st Semester
Course Code
Course Name
Credit
ECTS
BIO 201
Evolution and Biodiversity
Darwinian perspective of evolution, phylogeny, sources of genetic diversity, natural selection, genetic drift, gene flow, population genetics, species concept, history of life on earth, tree of life, animal, plant and microbial diversity, ecology. Prerequisitenone
3
6
BIO 203
Biostatistics
Measurements; Data analysis and organization; Biological and Statistical variables; Samples and populations; Descriptive statistics: central tendency, dispersion, standard error, confidence limits; Graphical display of data; Concepts of probability; Probability distributions; Hypothesis testing and inference: exact binomial tests, Chi-square tests, goodness of fit tests, Fisher’s test, Student’s t-test, ANOVA, MANOVA, Kruskal-Wallis test, Rank tests; Regression; Correlation; Contingency tables; Power analysis.
3
6
CHEM 241
Organic Chemistry for Engineering and Life Sciences
Introduction to organic chemistry for engineering and life science majors. Subjects covered include alkanes, alkenes, alkynes, isomerism, resonance, aromatic compounds and substitution reactions. This course satisfies the prerequisite requirements for CHEM 214. Prerequisite: CHEM 102. PrerequisiteCHEM 104
4
6
HSS
Humanities and Social Sciences Elective
see https://registration.boun.edu.tr/ for a full list of HSS courses
3
6
PHYS 201
Physics III
Charge and matter, the electric field, Gauss law, electrostatic potential,capacitance, current and resistance electromotive force and circuits, the magnetic field, Ampére’s law, Faraday’s law, inductance, magnetic properties of matter. PrerequisitePHYS 101
4
6
TK 221
Turkish for Native Speakers I
Theories of language, the emergence of language and language-culture relationship, Turkish Ural-Altay language family, the language which is the branch of linguistics that special attention should be given to the classification of four basic phonetics, morphology, syntax and semantics in Turkish language sound structure, word structure (suffix, root, trunk, etc.), grammatical topics such as sentence structure and the study of what has been Deciphered Decipherably to be taught during the semester (essays, poems, novels, short stories) are among the objectives of this course among the books of classical and contemporary Turkish authors.
2
3
2nd Semester
Course Code
Course Name
Credit
ECTS
BIO 204
Introduction to Bioinformatics
Genomic information; biological databases and data retrieval; genome browsers; sequencing technologies, assembly and annotation; sequence alignment algorithms; phylogenetic analysis; gene expression analysis; genetic variation analysis.
3
6
BIO 252
Genetics
Genes, genomes and genetic analysis; DNA structure and genetic variation; Mendelian genetics and its applications; chromosomes and sex-chromosome inheritance; genetic linkage; chromosome mapping, human karyotypes, chromosome behavior; extranuclear inheritance, molecular evolution, population genetics.
3
6
BIO 254
Genetics Laboratory
Use of restriction enzyme digestion in genetic linkage analysis; Drosophila as a model organism; monohybrid and dihybrid cross; polytene chromosome and karyotype analysis; polygenic inheritance and complex traits; fluorescence in situ hybridization, (FISH); bacterial conjugation and transduction; complementation; candidate gene approach. PrerequisiteCorequisite: BIO 252
3
6
HSS
Humanities and Social Sciences Elective
see https://registration.boun.edu.tr/ for a full list of HSS courses
3
6
MATH 201
Matrix Theory
Systems of linear equations, Gaussian elimination, matrix algebra determinants, inverse of a matrix, Cramer's rule, rank and nullity, the eigenvalue problem, introduction to linear programming. Prerequisitenone
4
5
TK 222
Turkish for Native Speakers II
Turkish expressing my article, identification, discussion and practical training for expression, punctuation, and Basic Rules of writing, spelling, and composition observed in the composition of students in the techniques of Correction of disorders of the expression and punctuation errors, reports, examples of the types of scientific writing such as articles, lectures and debates to give practical instruction in the oral studies and applications are covered in this section. In addition, the study of the books of classical and contemporary Turkish authors that were Decisively Deciphered to be read during the period (essays, poems, novels, short stories) is also among the objectives of this course.
2
3
Third Year
1st Semester
Course Code
Course Name
Credit
ECTS
BIO 301
Biochemistry I
Molecules of life; structure and function of proteins; nucleic acids; DNA as genetic material; flow of genetic information; enzymes; membrane structure and dynamics; membrane channels and pumps.
4
6
BIO 311
Cellular and Molecular Biology III
Analysis of cells, molecules and systems. Visualization of cells and their molecules. Intracellular organization and sorting. Intracellular membrane traffic. Cell signaling. Function and dynamics of the cytoskeleton. The cell cycle. PrerequisiteBIO 102
4
6
BIO 321
Research Topics in Molecular Biology
Presentations on the current research projects carried out in the Department.
1
2
BIO 333
Biochemistry Laboratory
Determination of pK of amino acids, cell disruption techniques, centrifugation techniques, sucrose gradient centrifugation, dialysis, chromatography techniques, SDS- PAGE electrophoresis; spectrophotometric measurement of protein and nucleic acid concentration; determination of protein amounts by Bradford assay, Western Blotting; thinlayer chromatography; Michaelis Menten kinetics PrerequisiteCorequisite: 301
3
6
BIO 353
Molecular Genetics
Chemistry of the gene; DNA replication and recombination; transcription; translation; mutation; control of gene regulation; transposable elements; genetics of bacteria and phages; gene cloning and manipulation. PrerequisiteBIO 102
4
6
HTR 311
History of the Turkish Republic I
A general survey of Turkish history from about the mid-19th century until World War II with a particular focus on the early Republican era. A comparative and analytical account of Westernization and Ottoman reform attempts, the struggle for constitution, the economic and social transformations, diplomacy and foreign policy, World War I, the rise of Turkish nationalism, the National Struggle, Kemalist social, economic and cultural reforms in the 1920s and 1930s with special emphasis on the Kemalist principles.
2
3
2nd Semester
Course Code
Course Name
Credit
ECTS
BIO 302
Biochemistry II
Catabolism and generation of phosphate bond energy; glycolysis; TCA cycle; oxidative phosphorylation; oxidation of fatty acids and oxidative degradation of amino acids; photosynthesis; biosynthesis of carbohydrates, lipids, amino acids and nucleotides.
4
6
BIO 308
Seminar I
Introduction to understanding and interpretation of research articles in the areas of molecular biology and genetics.
1
2
BIO 312
Cellular and Molecular Biology IV
Cell death. Cell junctions and the extracellular matrix. Cancer. Development of multicellular organisms. Stem cells in tissue homeostasis and regeneration. The innate and adaptive immune systems. PrerequisiteBIO 102, BIO 311
3
6
BIO 342
Human Physiology
Homeostatic control mechanisms; nerve cell physiology; central nervous system; peripheral nervous system; muscle physiology; cardiovascular physiology; blood and hematopoiesis; respiration and gas exchange; the kidneys; fluid and electrolyte balance; digestion and absorption of food; metabolism and energy balance; endocrine system; endocrine control of metabolism
3
6
BIO 356
Molecular Biology Laboratory
How to use databases; primer design; construction of bacterial growth curves; competant bacterial cell preparation; plasmid DNA isolation; agarose gel electrophoresis; Polymerase Chain Reaction (PCR); purification of plasmid vector and PCR products, digestion with restriction enzymes, ligation, and transformation; screening with colony PCR; transfection of eukaryotic cells with the vector; microscopic visualization of fluorescently tagged proteins; quantitative Real Time PCR and DNA sequencing. PrerequisiteCorequisite: BIO 353
3
6
HTR 312
History of the Turkish Republic II
A general survey of Turkish history from the beginning of World War II until the present. A comparative and analytical account of party-politics, social movements and mobilizations; different interpretations of Kemalism, the problems of urbanization, industrialization, and immigration; cultural and ideological changes, Turkey's foreign policy and an overall assessment of Turkey's standing in light of national and international developments.
2
3
Fourth Year
1st Semester
Course Code
Course Name
Credit
ECTS
BIO 403
Scientific Conduct
Responsible conduct of research (RCR): Collaborative Science, Conflicts of interests and commitment; data acquisition, management, sharing and ownership, ethical regulations in research involving human and animal subjects, mentoring; Peer review Publication practices and responsible authorship; research misconduct.
2
3
BIO 407
Seminar II
Student presentation and discussions of research articles covering various areas of molecular biology and genetics such as development, cancer, genomics.
2
3
BIO xxx
Department Elective
to be chosen from 400 level BIO elective courses
3
6
XXX
Complementary / Department Elective
to be chosen from 400 level BIO electives or related subjects
3
6
XXX
Unrestricted Elective
3
6
XXX
Unrestricted Elective
3
6
2nd Semester
Course Code
Course Name
Credit
ECTS
BIO xxx
Departmental Elective
to be chosen from 400 level BIO elective courses
3
6
BIO xxx
Departmental Elective
to be chosen from 400 level BIO elective courses
3
6
XXX
Unrestricted Elective
3
6
XXX
Complementary / Departmental Elective
to be chosen from 400 level BIO elective courses or related fields
3
6
XXX
Unrestricted Elective
3
6
3
6